Forging Health Partnerships Under the Trump Administration’s America First Global Health Strategy in Honduras and Senegal

The United States signed bilateral health cooperation Memoranda of Understanding (MOUs) with the Republic of Honduras and the Republic of Senegal, marking significant milestones in advancing the Trump Administration’s America First Global Health Strategy while strengthening our partnerships in the Western Hemisphere and Africa.

In Honduras, the Department of State signed a five-year, $46.5 million bilateral health MOU which includes $29.6 million in U.S. investment and $16.9 million in Honduran co-investment—of which $9.6 million is dedicated to Global Health Security.  The MOU integrates the transition of HIV/AIDS programming with strengthened infectious disease outbreak preparedness, with the goal of enabling Honduras to detect outbreaks within seven days, notify the United States within one day, and initiate a response within seven days by 2030.

Strategic investments will support laboratory capacity, epidemiological surveillance, supply chain modernization, the National Referral and Response System (SINARR), and the introduction of innovative American technologies such as lenacapavir.  Honduras will also decrease dependency on U.S. foreign assistance by absorbing 95 U.S.-funded frontline healthcare workers and 14 laboratory staff into its own payroll by 2028, while gradually assuming procurement of HIV-related commodities and laboratory supplies.

In Senegal, the Department of State signed a five-year health cooperation MOU totaling $90.4 million.  The Department of State, working with Congress, intends to provide $63.1 million to fight HIV and malaria, support health governance, laboratory capacity, health facility upgrades, and digital health systems advancement. Senegal commits to invest $27.3 million in co-financing.  Senegal’s strategic objectives prioritize expanding health coverage, strengthening governance through quality control and establishing a new National Institute of Public Health, advancing digital health transformation with electronic patient records and telemedicine, and achieving pharmaceutical sovereignty by producing 30 percent of medicines locally using government of Senegal funds.

The MOU also includes $15.7 million in global health security funding to improve health governance, enhance laboratory capacity, upgrade health facilities, and advance digital health systems—critical investments that will strengthen Senegal’s ability to detect and respond to infectious disease outbreaks that could threaten both Senegalese and American populations.

America First Global Health Strategy Memoranda of Understanding (MOUs) signed so far represent more than $20.4 billion in new health funding including more than $12.6 billion in U.S. assistance alongside $7.7 billion in co-investment from recipient countries, building on decades of progress fighting HIV/AIDS, malaria, tuberculosis, and other infectious diseases around the world.  As of March 13, the State Department has signed 26 bilateral global health MOUs with Botswana, Burkina Faso, Burundi, Cameroon, Côte d’Ivoire, the Democratic Republic of the Congo, the Dominican Republic, El Salvador, Eswatini, Ethiopia, Guatemala, Guinea, Honduras, Kenya, Lesotho, Liberia, Madagascar, Malawi, Mozambique, Niger, Nigeria, Panama, Rwanda, Senegal, Sierra Leone, and Uganda.